P78: Depakine Improve Axonal Growth In Vitro and In Vivo after Spinal Cord Injury
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p78: depakine improve axonal growth in vitro and in vivo after spinal cord injury
central nervous system axons fail to regenerate after spinal cord injury (sci), partially due to the accumulation of extracellular matrix molecules in the lesion and formation of the glial scar. depakine, as known as histone deacetylase inhibitor, has neuroprotective effects. this study evaluated the histological changes (cavitation and axon regeneration) after sci associated with (following ad...
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Spinal cord injury results in a life-disrupting series of deleterious interconnected mechanisms encompassed by the primary and secondary injury. These events are mediated by the upregulation of genes with roles in inflammation, transcription, and signaling proteins. In particular, cytokines and growth factors are signaling proteins that have important roles in the pathophysiology of SCI. The ba...
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Journal title
volume 2 issue 4
pages 128- 128
publication date 2014-12
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